Ropivacaine inhibits proliferation, migration, and invasion while inducing apoptosis of glioma cells by regulating the SNHG16/miR-424-5p axis

Liu Rong; Wu Min; Xu Guiju; Ju Lu; Xiao Jinhui; Zhong Wei; He Xiao; Yang Yan

doi:10.1515/biol-2020-0108

Open Life Sciences (Dec 2020)

Ropivacaine inhibits proliferation, migration, and invasion while inducing apoptosis of glioma cells by regulating the SNHG16/miR-424-5p axis

Liu Rong,
Wu Min,
Xu Guiju,
Ju Lu,
Xiao Jinhui,
Zhong Wei,
He Xiao,
Yang Yan

Affiliations

Liu Rong: Department of Anesthesiology, The 908th Hospital of Chinese PLA Logistical Support Force, No.4, Hudong Road, Yuehu District, Yingtan 335000, Jiangxi, China
Wu Min: Department of Anesthesiology, The 908th Hospital of Chinese PLA Logistical Support Force, No.4, Hudong Road, Yuehu District, Yingtan 335000, Jiangxi, China
Xu Guiju: Department of Anesthesiology, The 908th Hospital of Chinese PLA Logistical Support Force, No.4, Hudong Road, Yuehu District, Yingtan 335000, Jiangxi, China
Ju Lu: Department of Anesthesiology, The 908th Hospital of Chinese PLA Logistical Support Force, No.4, Hudong Road, Yuehu District, Yingtan 335000, Jiangxi, China
Xiao Jinhui: Department of Anesthesiology, The 908th Hospital of Chinese PLA Logistical Support Force, No.4, Hudong Road, Yuehu District, Yingtan 335000, Jiangxi, China
Zhong Wei: Department of Internal Medicine, Ruijin Hospital of traditional Chinese Medicine, Ruijin, Jiangxi, 342500, China
He Xiao: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, No.128, Jinling Road, Golden Development Zone, Ganzhou, Jiangxi, 341000, China
Yang Yan: Department of Anesthesiology, Ruijin Maternal and Child Health Hospital, Ruijin, Jiangxi, 342500, China

DOI: https://doi.org/10.1515/biol-2020-0108
Journal volume & issue: Vol. 15, no. 1
pp. 988 – 999

Abstract

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Regional anesthesia has anti-proliferative and pro-apoptotic effects in various cancers. Therefore, the purpose of this study was to investigate the effects of ropivacaine on the proliferation, migration, invasion, and apoptosis of glioma cells in vitro.

Published in Open Life Sciences

ISSN: 2391-5412 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: http://www.degruyter.com/view/j/biol

About the journal

Abstract

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