Fiyz̤ (Jan 2023)
Evaluation the relationship between serum lead levels and chronic constipation in children
Abstract
Background: Constipation refers to a condition in which intestinal movements are reduced and the passage of intestinal contents is difficult, and it is characterized by the involuntary retention of feces in children. One of the symptoms of lead poisoning is digestive symptoms, especially constipation. Although its role in gastrointestinal symptoms is known, little information is available on the effects of lower levels of lead on constipation. In this study, the effects of lower levels of lead poisoning in causing chronic constipation are investigated. Materials and Methods: This is a case-control study that was conducted on 30 children aged 1 to 14 years who were referred to the pediatric clinic of Shahid Beheshti Hospital in Kashan with complaints of defecation problems during the first six months of 2013. According to Rome 3 criteria, they had a chronic disease and were eligible to enter the study (according to the entry and exit criteria) and done. The control group was selected from among healthy children by matching age, gender, and place of residence. Results: The mean serum lead level in the study group and the control group was 9.11±4.04 and 6.36±2.94 micrograms/dL, respectively (P=0.004) and the frequency of lead poisoning was more than 10 µg/dl in the case group and 46.7% and 13.3% in the control group (P=0.005). Conclusion: The serum level of lead in children with chronic constipation is significantly higher than in healthy children.
