Communications Biology (Dec 2022)
An integrated map of fibroblastic populations in human colon mucosa and cancer tissues
- Siying Li,
- Ran Lu,
- Linjuan Shu,
- Yulin Chen,
- Jin Zhao,
- Junlong Dai,
- Qiaorong Huang,
- Xue Li,
- Wentong Meng,
- Feiwu Long,
- Yuan Li,
- Chuanwen Fan,
- Zongguang Zhou,
- Xianming Mo
Affiliations
- Siying Li
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Ran Lu
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Linjuan Shu
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Yulin Chen
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Jin Zhao
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Junlong Dai
- Department of Liver Surgery, West China Hospital, Sichuan University
- Qiaorong Huang
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Xue Li
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Wentong Meng
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Feiwu Long
- Department of Gastrointestinal, Bariatric and Metabolic Surgery, Research Center for Nutrition, Metabolism & Food Safety, West China-PUMC C.C. Chen Institute of Health, West China Fourth Hospital, West China School of Public Health, Sichuan University
- Yuan Li
- Institute of Digestive Surgery and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University
- Chuanwen Fan
- Department of Gastrointestinal, Bariatric and Metabolic Surgery, Research Center for Nutrition, Metabolism & Food Safety, West China-PUMC C.C. Chen Institute of Health, West China Fourth Hospital, West China School of Public Health, Sichuan University
- Zongguang Zhou
- Institute of Digestive Surgery and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University
- Xianming Mo
- Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- DOI
- https://doi.org/10.1038/s42003-022-04298-5
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 14
Abstract
The heterogeneity of fibroblasts in normal colon mucosa and colorectal cancer (CRC) is examined using single cell data, showing their potential function in normal gut homeostasis and in CRC.
