Comparison of osteoporosis frequency in female patients with non-radiographic axial spondyloarthritis and ankylosing spondylitis

Abstract

Objective: The aim of this study is to determine of the frequency of osteoporosis in patient with non-radiographic axial spondyloarthritis (SpA) and ankylosing spondilitis. The correlation between frequency of osteoporosis and disease activity and severity will be investigated in these patient. Methods: The study retrospectively inculede 53 patients with non-radiographic axial SpA, 43 patients with ankylosing spondilitis diagnosed according modified new york criteria and 61 healthy volunteers, who her admitted to the Ankara Atatürk Researc hospital rheumatology deparment between november 2013 and may 2015. Results: In the patient group with Ankylosing spondilitis, osteoporosis was detected in 7 patient (16.3%) osteopenia was detected in 16 patient (37.2%) and 20 patient is normal (46.5%). In the non-radiographic axial SpA group 4 patient had osteporosis (7.5%), 18 patient (34.0%) had osteopenia and 31 patient (58.5%) had normal. Osteporosis was detected in 4 (6.6%) of the total 61 patient in the control group, osteopenia was detected in 28 (45.9%), while bone mineral densitometry was normal in 29 patient (47.5%). Conclusion: In our study frequency of osteoporosis in both ankylosing spondilitis and non-radiographic axial SpA was found to be close and no statistically significant difference was observed. We can recommend that who are followed up with non-radiographic axial SpA be screened for osteoporosis during the follow-up periods. Randomized, prospective studies with a large number of patients will increase our knowledge on this subject.

Keywords

• axial spondyloarthritis
• non-radiographic axial spondyloarthritis
• osteoporosis