肥胖对卒中预后的影响 The Effect of Obesity on Prognosis of Stroke

Abstract

肥胖被认为是卒中的危险因素，但肥胖对卒中预后影响的研究却存在矛盾结果，有研究显示肥胖对卒中患者的预后有不利影响，但也有研究显示肥胖和超重的卒中患者可获得更好的预后，卒中患者的BMI和死亡率之间存在反比关系的“肥胖悖论”。了解肥胖与卒中患者的预后有助于帮助临床医师制订个体化的诊疗方案，以及指导疾病预防。因此，本文综述肥胖与卒中预后的相关研究及进展，旨在探讨肥胖界定标准、卒中类型、卒中病情及病程以及预后指标等因素对研究结论的可能影响，为卒中诊治提供参考，指导未来研究方向。 Abstract: Obesity is considered as a risk factor for stroke, but its effect on the prognosis of stroke is still unclear, even there is a “obesity paradox”. That is, there is an inverse relationship between the BMI and mortality of stroke patients. Understanding the effect of obesity on the prognosis of patients with stroke is helpful for clinicians to formulate individualized treatment and guide stroke prevention. Therefore, this article mainly reviewed the progress of the effect of obesity on stroke prognosis, and analyzed the possible factors affecting the conclusions, such as the definition standard of obesity, type of stroke, stroke course and severity, prognosis and other factors, to provide reference for the future research.

Keywords

• 卒中
• 肥胖
• 体重指数
• 肥胖悖论
• 预后
• stroke
• obesity
• body mass index
• obesity paradox
• prognosis