Ukrainian Neurosurgical Journal (Mar 2008)

Study of antiblastic activity of ukrain and cisplatin in the experiment on the model of transplanted brain glioma (stamm 101.8)

  • V. M. Semenova,
  • N. I. Lisyaniy,
  • G. E. Chitaeva,
  • A. I. Klyuchnikova,
  • A. N. Lisyaniy,
  • L. M. Behlskaya,
  • O. V. Shevchuk

DOI
https://doi.org/10.25305/unj.108865
Journal volume & issue
no. 1
pp. 32 – 37

Abstract

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On the model of experimental malignant rats’ brain glioma (stamm 101.8) efficiency of antiblastic medicine of plant origin ukrain was compared to cisplatin. At rats with glioma, treated with ukrain and cisplatin, the reliable increase of animals life-span on 33–37,5% compared with control index, was obtained. In brain glioma tissue signs of cytodestructive and citostatic influence of medicines been tested, were observed, more expressed at cisplatin application.