Prevalence and characteristics of gastric remnant cancer: A systematic review and meta-analysis

Tsz Kin Mak, MD; Bingsheng Guan, MD; Juzheng Peng, MD; Tsz Hong Chong, MD; Cunchuan Wang, MD, PhD; Shifang Huang, MD, PhD; Jingge Yang, MD, PhD

Asian Journal of Surgery (Jan 2021)

Prevalence and characteristics of gastric remnant cancer: A systematic review and meta-analysis

Tsz Kin Mak, MD,
Bingsheng Guan, MD,
Juzheng Peng, MD,
Tsz Hong Chong, MD,
Cunchuan Wang, MD, PhD,
Shifang Huang, MD, PhD,
Jingge Yang, MD, PhD

Affiliations

Tsz Kin Mak, MD: Department of Gastrointestinal Surgery, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China
Bingsheng Guan, MD: Department of Gastrointestinal Surgery, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China
Juzheng Peng, MD: Department of Gastrointestinal Surgery, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China
Tsz Hong Chong, MD: Department of Gastrointestinal Surgery, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China
Cunchuan Wang, MD, PhD: Department of Gastrointestinal Surgery, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China
Shifang Huang, MD, PhD: Department of Internal Medicine, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Corresponding author.
Jingge Yang, MD, PhD: Department of Gastrointestinal Surgery, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Corresponding author.

Journal volume & issue: Vol. 44, no. 1
pp. 11 – 17

Abstract

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The incidence and outcomes of GRC remain variable. Minority published researches have paid attention to the characteristics of GRC. This study aimed to make a systematic review and meta-analysis of the prevalence of GRC, with a focus on characteristics and survival rates of GRC. PubMed, EMBASE, and CENTRAL were searched for related clinical studies. Data were pooled using Stata 11.0, and subgroup and sensitivity analyses were performed if necessary and feasible. Moreover, SPSS (version 19.0) was used for comparing the clinical characteristics of GRC. Twenty studies were selected in this meta-analysis. The results indicated that the pooled prevalence of GRC was 2.6% (95% confidence interval (CI), 2.2–3.0%, p = 0.000). European population and American populations have a higher rate of prevalence of GRC than Chinese populations and Japan. There is no significant difference in histology and the TNM stage between the benign group and the malignant group. The five-year survival rate for GRC cases with benign primary gastric diseases is poorer than the primary gastric diseases malignant. Gastric remnant cancer is not a very rare clinical problem, especially for European and American patients. Active treatment and regular follow-up are conductive to increase 5-years survival rate.

Published in Asian Journal of Surgery

ISSN: 1015-9584 (Print)
Publisher: Elsevier
Country of publisher: Hong Kong
LCC subjects: Medicine: Surgery
Website: http://www.journals.elsevier.com/asian-journal-of-surgery/

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