ASSESSMENT OF CLINICAL EFFICACY OF EXTENSIVELY HYDROLYZED CASEIN FORMULA IN DIETOTHERAPY OF SEVERE FORMS OF INTOLERANCE TO COW’S MILK PROTEIN IN CHILDREN

Abstract

The cause of alimentary allergy in infants is most common associated with different fractions of cow milk protein intolerance. As the milk component plays significant role in the diet of healthy infants and young children, the dietotherapy is based on special products — hydrolyzed formulas. The authors performed a research on assessment of the clinical efficacy of extensively hydrolyzed casein formula. This formula was given to 46 children at the age of 2–12 months with moderate (SCORAD ≥ 20) and severe (SCORAD ≥ 50) index of alimentary allergy manifestations. At the beginning of the investigation the increasing of serum IgE 5–10 times as normal was found in 73% of examined children. At the final follow-up the improvement of cutaneous symptoms, lowering of serum IgE were found in 96,2% of children, in 68% clinical remission was confirmed.

Keywords

• infants
• allergy to cow milk proteins (cow milk proteins intolerance)
• dietotherapy
• extensively hydrolyzed casein formulas