Evaluation of relationship between periodontitis and various components of metabolic syndrome

Abstract

Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that include obesity, diabetes, hypertension, and dyslipidemia. Oxidative stress may act as a common link to explain the relationship between each component of MetS and periodontitis. MetS is characterized by oxidative stress, a condition in which the equilibrium between the production and the inactivation of reactive oxygen species (ROS) becomes disrupted. ROS contribute to cellular dysfunction and damage. Patients with more components of MetS had a significantly greater probing depth and clinical attachment loss. Evaluation of relationship between periodontitis and various components of Metabolic syndrome (MetS).This prospective study was carried out on study group consists of 30 subjects. All the patients will be evaluated for the risk factors of MetS which are: B.M.I., B.R, Triglycerides, R.B.S. increase in these risk factors is associated with increase in periodontal pocket depth, gingival recession and clinical loss of attachment. Metabolic alterations related to MetS causes an augmented response to bacterial plaque favouring periodontal insurgence. Oxidative stress acts as common link to explain the relationship between each component of MetS and periodontitis. Thus, periodontitis the harbinger of MetS which is more severe and disproportionate to number of local factors related to it.

Keywords

• metabolic syndrome. oxidative stress. periodontitis