Nature Communications (Feb 2020)

miRNA-1-3p is an early embryonic male sex-determining factor in the Oriental fruit fly Bactrocera dorsalis

  • Wei Peng,
  • Shuning Yu,
  • Alfred M. Handler,
  • Zhijian Tu,
  • Giuseppe Saccone,
  • Zhiyong Xi,
  • Hongyu Zhang

DOI
https://doi.org/10.1038/s41467-020-14622-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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In insects, Y chromosome-linked male determining factor can determine sex, but the sex determination factor of the Oriental Fruit fly is unknown. Here the authors show that an autosomal-derived miR-1-3p is enriched in males, suppressing the expression of Bdtra, which is required for female sex determination.