Copper-catalyzed O-alkenylation of phosphonates

Abstract

Copper catalysis allows the direct oxygen alkenylation of dialkyl phosphonates with alkenyl(aryl)iodonium salts with selective transfer of the alkenyl group. This novel methodology proceeds with a wide range of phosphonates under mild conditions and gives straightforward access to valuable enol phosphonates in very good yields.

Keywords

• alkenylation
• copper
• c(sp2)–o bond formation
• hypervalent iodine
• phosphonates