Journal of Association of Pulmonologist of Tamil Nadu (Jan 2019)

Ubiquitous Fungus Irking Inclined Wheezers - A succinct on Allergic Bronchopulmonary Aspergillosis

  • Amal Johnson,
  • Vaseema Thabassum,
  • R Narasimhan

DOI
https://doi.org/10.4103/WKMP-0215.309241
Journal volume & issue
Vol. 2, no. 2
pp. 62 – 68

Abstract

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Aspergillus mold cause respiratory disease depending upon the host immunity and organism virulence. ABPA is the most significant manifestation of allergic aspergillosis. It is an immunological pulmonary disease caused by hypersensitivity reaction to the aspergillus antigen in susceptible patients, most commonly with asthma and cystic fibrosis. The presentation can range from mild symptoms to extensive lung disease that may manifest as respiratory failure. This review summarizes the history, epidemiology, risk factors, immunopathogenesis, pathology, clinical features, diagnostic criteria, laboratory and radiological investigations and management of ABPA.

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