Neurexins regulate presynaptic GABAB-receptors at central synapses

Fujun Luo; Alessandra Sclip; Sean Merrill; Thomas C. Südhof

doi:10.1038/s41467-021-22753-5

Nature Communications (Apr 2021)

Neurexins regulate presynaptic GABAB-receptors at central synapses

Fujun Luo,
Alessandra Sclip,
Sean Merrill,
Thomas C. Südhof

Affiliations

Fujun Luo: Department of Molecular and Cellular Physiology and Howard Hughes Medical Institute, Stanford University Medical School
Alessandra Sclip: Department of Molecular and Cellular Physiology and Howard Hughes Medical Institute, Stanford University Medical School
Sean Merrill: Department of Molecular and Cellular Physiology and Howard Hughes Medical Institute, Stanford University Medical School
Thomas C. Südhof: Department of Molecular and Cellular Physiology and Howard Hughes Medical Institute, Stanford University Medical School

DOI: https://doi.org/10.1038/s41467-021-22753-5
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 13

Abstract

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Neurexins are evolutionarily conserved cell adhesion molecules that tune synapse formation and specification. Here the authors show that neurexins play similar roles in regulating presynaptic GABAB receptors at multiple CNS synapses.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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