Evaluation of Serum Vitamin-D Levels in Patients with Alopecia Areata

Abstract

Objective: To evaluate serum vitamin-D levels in patients with Alopecia areata compared to healthy controls. Study Design: Comparative cross-sectional study. Place and Duration of Study: Dermatology Outpatient Department, Fauji Foundation Hospital, Rawalpindi Pakistan, from Nov 2019 to Apr 2020. Methodology: The study included 70 patients with Alopecia areata (Group-1) and 70 healthy controls (Group-2). Complete blood count, TSH, urea and creatinine, fasting plasma glucose, liver function tests, serum Calcium and vitamin-D levels were performed. Results: The mean vitamin-D levels of Group-1 were 38.28±22.07ng/mL, and the mean vitamin-D levels of Group-2 were 39.61±18.36ng/mL. In Group-1, deficient vitamin-D levels were seen in 14(20.0%) of Group-1, and insufficient in 19(27.1%) and 37(52.9%) had normal levels. In Group-2, 10(14.3%) had deficient levels, 16(25.0%) had insufficient levels and 44(62.9%) had normal levels. No statistically significant difference seen between Group-1 and Group-2. Conclusion: There is no association between vitamin D level and Alopecia Areata.

Keywords

• Alopecia areata
• Autoimmune diseases
• Vitamin-D deficiency