Effect of fullerene C(60) on ATPase activity and superprecipitation of skeletal muscle actomyosin

Abstract

Creation of new biocompatible nanomaterials, which can exhibit the specific biological effects, is an important complex problem that requires the use of last accomplishments of biotechnology. The effect of pristine water-soluble fullerene C60 on ATPase activity and superprecipitation reaction of rabbit skeletal muscle natural actomyosin has been revealed, namely an increase of actomyosin superprecipitation and Мg2+, Са2+– and K+-ATPase activity by fullerene was investigated. We conclude that this finding offers a real possibility for the regulation of contraction-relaxation of skeletal muscle with fullerene C60.

Keywords

• atomic-force microscopy
• ATPase activity
• fullerene C(60)
• molecular docking
• skeletal muscle natural actomyosin
• superprecipitation