Biofilm Formation by Quorum Sensing and Manners to Deal It

Abstract

Relationship between microorganisms with chemical signals is called quorum sensing (QS). This process has been found in most microorganisms (gram negative and gram positive bacteria and also fungi). QS is required for different activities of microorganisms such as, virulence factor secretion, motility, competence, biofilm and sporulation. There are different molecules as signals in disparate microorganisms. Biofilm formation is one of the significant functions of QS. Biofilms are groups of microorganisms that are tied to a surface (biotic or abiotic). One of the remarkable roles of biofilm is creation persistent bacteria. Biofilm formed in most of pathogen microorganisms and play the main role in their pathogenicity. Many studies had been done about QS, biofilm formation and ways against biofilm formation. These studies could help to the removal of microorganisms that formed biofilm. Here we describe QS and biofilm formation in some important microorganisms and suggested ways to eradicating biofilm formation of them.

Keywords

• Quorum Sensing
• Biofilm Formation
• Pseudomonas aeruginosa
• Listeria monocytogenes
• Burkholderia cepacia
• Staphylococcus aureus