Разработка и регистрация лекарственных средств (Jan 2019)
ULTRASTRUCTURE OF RAT LIVER AND LUNGS AFTER SINGLE INTRAVENOUS INJECTION OF MAGNITOMICELLS BASED CARBON-COATED IRON NANOPARTICLES
Abstract
In this study the effect of magnitomicells based on carbon incapsulated iron nanoparticles on the ultrastructure of rat’s liver and lungs after intravenous injection of their aqueous suspensions was investigated. Deducing of animal from the experiment was conducted in 1st and 40th days after intravenous injection of suspensions of nanoparticles. Ultrastructural examination of the liver and lung of rats was performed with a transmission electron microscope. Ultrastructural signs of damage of hepatocytes, pneumocytes and mononuclear phagocytes are not detected.