PLoS ONE (Jan 2023)

Hemodynamical consequences and tolerance of sustained ventricular tachycardia.

  • Hubert Delasnerie,
  • Caroline Biendel,
  • Meyer Elbaz,
  • Franck Mandel,
  • Maxime Beneyto,
  • Guillaume Domain,
  • Quentin Voglimacci-Stephanopoli,
  • Pierre Mondoly,
  • Clement Delmas,
  • Vanina Bongard,
  • Anne Rollin,
  • Philippe Maury

DOI
https://doi.org/10.1371/journal.pone.0285802
Journal volume & issue
Vol. 18, no. 5
p. e0285802

Abstract

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AimsFactors underlying clinical tolerance and hemodynamic consequences of monomorphic sustained ventricular tachycardia (VT) need to be clarified.MethodsIntra-arterial pressures (IAP) during VT were collected in patients admitted for VT ablation and correlated to clinical, ECG and baseline echocardiographical parameters.Results114 VTs from 58 patients were included (median 67 years old, 81% ischemic heart disease, median left ventricular ejection fraction 30%). 61 VTs were untolerated needing immediate termination (54%). VT tolerance was tightly linked to the evolution of IAPs. Faster VT rates (pConclusionThis study helps to explain the large variability in clinical tolerance during VT, which is clearly related to IAP. VT tolerance may be linked to resynchronization therapy, VT rate, baseline QRS duration and location of myocardial infarction.