Phenylseleno trifluoromethoxylation of alkenes

Abstract

Trifluoromethoxylated molecules and selenylated compounds find a wide range of interesting applications, but separately. In order to combine the potential of these two motifs and to propose a new class of compounds, we have developed an electrophilic phenylseleno trifluoromethoxylation of alkenes, which leads to β-selenylated trifluoromethoxylated compounds or, upon subsequent reduction, to the trifluoromethoxylated ones.

Keywords

• dntfb
• electrophilic addition
• fluorine
• selenium
• trifluoromethoxy