Primary Squamous Cell Carcinoma of Thyroid Gland: A Report of Two Cases

Abstract

Primary squamous cell carcinoma of the thyroid gland (PSCCT) is a rare malignancy seen in <1% of all primary malignancies of the thyroid gland, and it carries a poor prognosis. The patient usually presents with metastasis at the time of the presentation. Here, we report two cases of PSCCT. On clinical assessment, both the cases were considered as suspicious for malignancy. Radiological investigations showed a nodular lesion measuring 5 cm × 3.5 cm × 2 cm with internal vascularity in the first case while large multilobulated mass measuring 8.4 cm × 8.3 cm × 5.6 cm compressing the surrounding structures in the second case. Both of the patients underwent surgical interventions. The final diagnosis of PSCCT was made after thorough investigations excluding the possibility of primary focus elsewhere in the body. Both patients succumbed to death within 8 months. We report these two cases of PSCCT due to the rarity of this entity in literature.

Keywords

• primary squamous cell carcinoma
• thyroid gland
• thyroid malignancy