Internet Interventions (Apr 2022)
Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan
- Kazuki Matsumoto,
- Sayo Hamatani,
- Takuya Makino,
- Jumpei Takahashi,
- Futoshi Suzuki,
- Tomoko Ida,
- Shoko Hamamura,
- Shinichiro Takiguchi,
- Akemi Tomoda,
- Ichiro M. Omori,
- Hirotaka Kosaka,
- Seina Shinno,
- Tomoki Ikai,
- Hiroyuki Hayashi,
- Hiroto Katayama,
- Yuki Shiko,
- Yoshihito Ozawa,
- Yohei Kawasaki,
- Chihiro Sutoh,
- Eiji Shimizu
Affiliations
- Kazuki Matsumoto
- Research Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan; Laboratory of Neuropsychology, Institute of Liberal Arts and Science, Kanazawa University, Ishikawa 920-1192, Japan; Corresponding author at: Research Center for Child Mental Development, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba 260-8588, Japan.
- Sayo Hamatani
- Research Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan; Research Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan
- Takuya Makino
- Research Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan
- Jumpei Takahashi
- Research Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan
- Futoshi Suzuki
- Research Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan; Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan
- Tomoko Ida
- Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan
- Shoko Hamamura
- Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan
- Shinichiro Takiguchi
- Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan
- Akemi Tomoda
- Research Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan; Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan
- Ichiro M. Omori
- Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan
- Hirotaka Kosaka
- Research Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan; Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan; Department of Neuropsychiatry, University of Fukui, Fukui 910-1192, Japan
- Seina Shinno
- Department of Integrated Medical Sciences, Graduate School of Medicine, University of Fukui, Fukui 910-1192, Japan; Department of Integrated Advanced Medicine, Graduate School of Medicine, University of Fukui, Fukui 910-1192, Japan
- Tomoki Ikai
- Department of Primary Health Care, Faculty of Medicine, University of Fukui, Fukui 910-1192, Japan
- Hiroyuki Hayashi
- Department of Integrated Advanced Medicine, Graduate School of Medicine, University of Fukui, Fukui 910-1192, Japan; Department of Emergency and General Medicine, University of Fukui Hospital, Fukui 910-1192, Japan
- Hiroto Katayama
- Kokorotokarada Clinic Fukui, Fukui 910-0067, Japan
- Yuki Shiko
- Biostatistics Section Clinical Research Center, Chiba University Hospital, Chiba 260-8677, Japan
- Yoshihito Ozawa
- Biostatistics Section Clinical Research Center, Chiba University Hospital, Chiba 260-8677, Japan
- Yohei Kawasaki
- Biostatistics Section Clinical Research Center, Chiba University Hospital, Chiba 260-8677, Japan; Faculty of Nursing, Japanese Red Cross College of Nursing, Tokyo 150-0012, Japan
- Chihiro Sutoh
- Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba 260-8588, Japan
- Eiji Shimizu
- Research Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan; Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba 260-8588, Japan; Cognitive Behavioral Therapy Center, Chiba University Hospital, Chiba 260-8588, Japan
- Journal volume & issue
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Vol. 28
p. 100515
Abstract
Few studies have compared the effectiveness of internet-based cognitive behavior therapy (ICBT) for obsessive-compulsive disorder (OCD) with treatment as usual (TAU). We investigated the effectiveness of guided ICBT for patients with OCD. This prospective, randomized, controlled, assessor-blinded, multicenter clinical trial was conducted at three facilities in Japan from January 2020 to March 2021. Thirty-one patients with OCD as the primary diagnosis participated in the trial and were randomly assigned to either the intervention group or the control group. The primary outcome was the Yale–Brown obsessive-compulsive scale score; the assessors were blinded. Results of the analysis of covariance among the groups were significantly different between the groups (p < 0.01, effect size Cohen's d = 1.05), indicating the superiority of guided ICBT. The results suggest that guided ICBT is more effective than TAU for treating OCD. RCT registration: UMIN Clinical Trials Registry (UMIN000039375).
