Incidence and temporal trends of childhood type 1 diabetes between 1975 and 2012 in Navarre (Spain)

Abstract

Objective: To determine trends in the incidence of type 1 diabetes in Navarre (Spain) between 1975 and 2012 by age and sex. Patients and methods: The study population comprised residents of Navarre under 15 years of age. A Poisson regression model was fitted to analyze changes in the incidence over time, adjusted by year of diagnosis, age group and sex. Results: A total of 494 patients were registered, representing an adjusted incidence rate of 13.2/100,000 person-years. The annual relative increase in the incidence rate was 3.7%. The highest incidence was found in the group aged 10–14 years. The incidence among boys aged 10–14 tended to be higher than that in girls of the same age. Conclusions: Since the year 2000, the incidence of type 1 diabetes among persons younger than 15 years in Navarre has been very high and has quadrupled over the last four decades.

Keywords

• Type 1 diabetes
• Incidence
• Trend
• Epidemiology