EVALUASI ADVERSE DRUG REACTION ANTIDIABETES BERDASARKAN ALGORITMA NARANJO DI BANGSAL RAWAT INAP RS PKU MUHAMMADIYAH YOGYAKARTA PERIODE DESEMBER 2011-JANUARI 2012

Abstract

This study is aimed to evaluated the antidiabetic adverse reaction using the Naranjo algorithm for diabetes mellitus patients in PKU Muhammadiyah Hospital Yogyakarta for period December 2011-January 2012. This study used descriptive method. The data was collected from the medical record and interviews from patients with diabetes mellitus who had used antidiabetic drugs after 3 days. The data were analyzed using the Naranjo algorithm. The results showed that during the period December 2011-January 2012 there were 17 male patients and 14 female patients with diabetes mellitus. The antidiabetic drugs that used to patients were metformin, metformin combined with glibenclamide, metformin combined with insulin, the combination with insulin and insulin glimepirid. Then, the study showed that Naranjo algorithm method was not suitable for evaluation the antidiabetic adverse reaction for diabetes mellitus patients in PKU Muhammadiyah Hospital in Yogyakarta for period December 2011-January 2012, because from 10 questions on the Naranjo algorithm there were only 4 questions that could be answered. It's because there was not data to answer questions. Research on the side effects cohort method should be done with the interview and patient monitoring.

Keywords

• Diabetes Mellitus
• Adverse drug reaction
• Naranjo algorithm