Cailiao gongcheng (Jan 2021)

Advances in antibacterial research based on two-dimensional nano-materials

  • ZHOU Xuan,
  • ZHENG Yun-fei,
  • JIA Qi-lin,
  • ZHANG Fei-ran

DOI
https://doi.org/10.11868/j.issn.1001-4381.2020.000360
Journal volume & issue
Vol. 49, no. 1
pp. 55 – 64

Abstract

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In recent years, antibiotic-resistant bacterial strains have spread rapidly and widely around the world. New antibacterial drugs have emerged to develop. With the development of biological nanotechnology, two-dimensional nanomaterials have become a very promising alternative for the treatment of antibiotic-resistant bacteria. Based on the recent literature, the structural features and antibacterial applications of graphene materials (GMs), transition-metal dichalcogedes (TMDs), layered double hydroxides (LDHs) and MXenes were elaborated, the antibacterial mechanisms of those materials were discussed, such as physical/mechanical damage, lipid extraction, oxidative stress, and photothermal/photodynamic effects,etc. Finally, the antibacterial research progress and challenges of two-dimensional nanomaterials were prospected:(1) 2D materials has a unique space structure and excellent biocompatibility, so it can be used as an ideal carrier for antibacterial drugs; (2) the material has photodynamic and photothermal bactericidal effects, so it has a strong potential to cure local skin infections; (3) it can be made into antibacterial coatings to achieve simple in-situ disinfection applying to sterile medical equipment in the future.

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