Toxic epidermal necrosis syndrome after taking nonsteroidal antiinflammatory drugs: a case report

Abstract

Introduction: Toxic epidermal necrolysis (TEN) is among the most severe forms of dermatological reactions, which often occurs in response to non-steroidal anti-inflammatory drugs (NSAIDs) and leads to death in 20-50% of the cases.  Case Presentation: A 41-year-old male patient was referred with a history of NSAID use, presenting with maculopapular rashes, at Kowsar Hospital in Sanandaj, Iran. The patient was hospitalized and received various therapies. He was discharged after 14 days in a good overall condition.  Conclusion: Determining the basic etiology and disruption of pharmaceutical factors are essential to the treatment of TEN. The therapeutic interventions are similar to those used for burn patients. Keywords: Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome, Non-steroidal Anti-inflammatory Drugs   

Keywords

• Toxic epidermal necrosis syndrome
• Stevens Johnson syndrome
• Nonsteroidal anti-inflammatory drugs