Compuestos Organometálicos y su potencial terapéutico en el tratamiento del cáncer. Una breve revisión

Abstract

According to the World Health Organization (WHO), cancer is the second cause of death in the world,almost one out of every six deaths globally is due to this disease. In chemistryarea, efforts are being made to better investigate anticancer compounds, and organometallic reagents offer an interesting opportunity, for a synergistic effect between the medicinal properties of the ligands and the chemical characteristics of the transition metals. In this article, we present a short review of some advances in anticancer organometallic compounds. The review indicates that small structural changesimplicate large changes in anticancer activity, which generates new possibilities more specific chemotherapies, with less side-effects and economically more affordable.

Keywords

• Agentes terapéuticos
• cáncer
• compuestos organometálicos
• ligantes
• metales de transición