The Turkish Journal of Pediatrics (Jan 2007)

Miller Fisher syndrome: a case with pattern of pure sensory polyneuropathy concomitant with anti-GQ1B antibody

  • Gülçin Akinci,
  • Muzaffer Polat,
  • Ayşe Tosun,
  • Gül Serdaroğlu,
  • Sarenur Gökben,
  • Hasan Tekgül

Journal volume & issue
Vol. 49, no. 1

Abstract

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Miller Fisher syndrome is characterized by the acute onset of ophthalmoplegia, ataxia, and areflexia. Anti-GQ1b antibodies are useful markers for the differential diagnosis of Miller Fisher syndrome. We describe the case of a seven-year-old male who presented with a four-day history of diplopia and ophthalmoplegia following a febrile flu-like illness with sore throat. On examination he was found to have ataxia, areflexia and ophthalmoplegia, and a diagnosis of Miller Fisher syndrome was made after the exclusion of other conditions and concomitant with electrophysiological findings on electromyography. Although this disorder has a rare incidence, it should still be considered in the differential diagnosis in our country.