New Evidence, Creative Insights, and Strategic Solutions: Advancing the Understanding and Practice of Diabetes Osteoporosis

Abstract

ABSTRACT Background Diabetes osteoporosis is a debilitating condition that significantly impacts human health. However, it is often underdiagnosed and not addressed in a timely or appropriate manner. Methods Recent studies were reviewed to explore the roles of energy metabolism, sarcopeina, low‐grade inflammation and gut microbiota in the development of diabetes osteoporosis. Results Osteoporosis in diabetic patients differs from primary osteoporosis. Novel biomarkers and risk factors that are biologically, physiologically, and pathologically linked to the development of diabetes osteoporosis are emerging, necessitating a shift in strategies for diagnosis, risk stratification, and prevention of diabetes osteoporosis. Conclusions There is an urgent need to approach this disorder from a fresh perspective, initiating a range of basic research and clinical investigations.

Keywords

• diabetes
• diagnosis
• fractures
• osteoporosis