Application of single-cell RNA sequencing technologies in aortic dilatation diseases

Abstract

Aortic dilation disease, represented by aortic dissection and aortic aneurysm, is the most dangerous disease in vascular surgery. The pathogenesis of this disease is not very clear. Single-cell RNA sequencing (scRNA-seq) technology can study cell heterogeneity and identify new cell states and populations at the single cell level, which provides a new tool for studying the occurrence and development mechanism of aortic disease.

Keywords

• aortic disease|single-cell rna sequencing|single-cell transcriptome sequencing|high throughput rna sequencing