Журнал инфектологии (Sep 2014)

Effectiveness of combined antyviral therapy in children with chronic hepatitis C

  • G. P. Martynova,
  • I. A. Solovyova,
  • T. A. Zhukovskaya,
  • A. B. Belkina,
  • Ya. A. Bogvilene,
  • I. A. Kutishcheva,
  • S. V. Evreimova

DOI
https://doi.org/10.22625/2072-6732-2013-5-2-37-42
Journal volume & issue
Vol. 5, no. 2
pp. 37 – 42

Abstract

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The paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic viral hepatitis C aged from 3 to 17, who underwent regular medical check-ups in City Clinical Hospital № 20 named after I.S. Berzon in Krasnoyarsk. Evaluation of effectiveness of combined antiviral therapy revealed that patients with genotype 1 had an immediate virologic response in 78,5% of cases, 83,3% of patients with genotype 2, 3 had a stable virologic response.

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