Modern concepts of pathogenesis and morphogenesis of pulmonary Langerhans’ cell histiocytosis of adults

Abstract

The article presents detailed information about modern pathogenetic mechanisms of pulmonary Langerhans’ cell histiocytosis of adults, as an isolated no neoplastic process, which in many moments of its development is uncontrolled abnormal immune response to a number of antigens not fully qualified by nature. Morphogenesis of pathology is described in details, as well as all stages of the disease, with emphasis on diagnostic morphological signs. Characteristic diagnostic biopsy microphotographs are presented. pulmonary Langerhans’ cell histiocytosis; pathogenesis; morphogenesis

Keywords

• pulmonary Langerhans’ cell histiocytosis
• pathogenesis
• morphogenesis