Analysis of Helicobacter pylori infection in patients with oral lichen planus

Abstract

Objective To explore the correlation between oral mucosal lichen planus and Helicobacter pylori infec⁃ tion by analyzing the infection status of Helicobacter pylori in patients with oral mucosal lichen planus. Methods 14C⁃ urea breath test was done in 69 patients with oral lichen planus and 28 patients with chronic inflammation of oral muco⁃ sa. Detection of serum anti Helicobacter pylori antibody was done in 32 patients (23 with oral lichen planus and 9 with chronic inflammation of oral mucosa) at the same time. Results The positive rate of 14C⁃urea breath test was 68.12% in patients with oral lichen planus and 46.43% in chronic inflammation of oral mucosa. There was significant difference between the 2 groups (c2 ＝3.970, P＝0.046). The positive rate of anti Helicobacter pylori antibody was 52.17% in pa⁃ tients with oral lichen planus and 22.22% in chronic inflammation of oral mucosa, and there was no significant differ⁃ ence between the 2 groups (c2 ＝2.358, P＝0.125). Conclusion The prevalence of Helicobacter pylori infection in pa⁃ tients with oral lichen planus is higher, and there is a relevance between oral lichen planus and Helicobacter pylori infec⁃ tion.

Keywords

• Oral lichen planus，
• Helicobacter pylori，
• 14C⁃urea breath test，
• Anti Hp antibody，
• Relevance，