Nature Communications (May 2021)
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
- Ge Song,
- Wan-ting He,
- Sean Callaghan,
- Fabio Anzanello,
- Deli Huang,
- James Ricketts,
- Jonathan L. Torres,
- Nathan Beutler,
- Linghang Peng,
- Sirena Vargas,
- Jon Cassell,
- Mara Parren,
- Linlin Yang,
- Caroline Ignacio,
- Davey M. Smith,
- James E. Voss,
- David Nemazee,
- Andrew B. Ward,
- Thomas Rogers,
- Dennis R. Burton,
- Raiees Andrabi
Affiliations
- Ge Song
- Department of Immunology and Microbiology, The Scripps Research Institute
- Wan-ting He
- Department of Immunology and Microbiology, The Scripps Research Institute
- Sean Callaghan
- Department of Immunology and Microbiology, The Scripps Research Institute
- Fabio Anzanello
- Department of Immunology and Microbiology, The Scripps Research Institute
- Deli Huang
- Department of Immunology and Microbiology, The Scripps Research Institute
- James Ricketts
- Department of Immunology and Microbiology, The Scripps Research Institute
- Jonathan L. Torres
- Department of Integrative Structural and Computational Biology, The Scripps Research Institute
- Nathan Beutler
- Department of Immunology and Microbiology, The Scripps Research Institute
- Linghang Peng
- Department of Immunology and Microbiology, The Scripps Research Institute
- Sirena Vargas
- Department of Immunology and Microbiology, The Scripps Research Institute
- Jon Cassell
- Department of Immunology and Microbiology, The Scripps Research Institute
- Mara Parren
- Department of Immunology and Microbiology, The Scripps Research Institute
- Linlin Yang
- Department of Immunology and Microbiology, The Scripps Research Institute
- Caroline Ignacio
- Division of Infectious Diseases, Department of Medicine, University of California, San Diego
- Davey M. Smith
- Division of Infectious Diseases, Department of Medicine, University of California, San Diego
- James E. Voss
- Department of Immunology and Microbiology, The Scripps Research Institute
- David Nemazee
- Department of Immunology and Microbiology, The Scripps Research Institute
- Andrew B. Ward
- IAVI Neutralizing Antibody Center, The Scripps Research Institute
- Thomas Rogers
- Department of Immunology and Microbiology, The Scripps Research Institute
- Dennis R. Burton
- Department of Immunology and Microbiology, The Scripps Research Institute
- Raiees Andrabi
- Department of Immunology and Microbiology, The Scripps Research Institute
- DOI
- https://doi.org/10.1038/s41467-021-23074-3
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Pre-existing immune responses between antigenically related viruses can influence responses in viral infections or vaccinations. Here the authors assess and characterize the presence of antibody and memory B cell populations specific to SARS-CoV2 and endemic human coronaviruses.
