PLoS Medicine (Apr 2019)

The incidence of pregnancy hypertension in India, Pakistan, Mozambique, and Nigeria: A prospective population-level analysis.

  • Laura A Magee,
  • Sumedha Sharma,
  • Hannah L Nathan,
  • Olalekan O Adetoro,
  • Mrutynjaya B Bellad,
  • Shivaprasad Goudar,
  • Salécio E Macuacua,
  • Ashalata Mallapur,
  • Rahat Qureshi,
  • Esperança Sevene,
  • John Sotunsa,
  • Anifa Valá,
  • Tang Lee,
  • Beth A Payne,
  • Marianne Vidler,
  • Andrew H Shennan,
  • Zulfiqar A Bhutta,
  • Peter von Dadelszen,
  • CLIP Study Group

DOI
https://doi.org/10.1371/journal.pmed.1002783
Journal volume & issue
Vol. 16, no. 4
p. e1002783

Abstract

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BackgroundMost pregnancy hypertension estimates in less-developed countries are from cross-sectional hospital surveys and are considered overestimates. We estimated population-based rates by standardised methods in 27 intervention clusters of the Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomised trials.Methods and findingsCLIP-eligible pregnant women identified in their homes or local primary health centres (2013-2017). Included here are women who had delivered by trial end and received a visit from a community health worker trained to provide supplementary hypertension-oriented care, including standardised blood pressure (BP) measurement. Hypertension (BP ≥ 140/90 mm Hg) was defined as chronic (first detected at ConclusionsPregnancy hypertension is common in less-developed settings. Most women in this study presented with gestational hypertension amenable to surveillance and timed delivery to improve outcomes.Trial registrationThis study is a secondary analysis of a clinical trial - ClinicalTrials.gov registration number NCT01911494.