European Journal of Obstetrics & Gynecology and Reproductive Biology: X (Mar 2025)

Management of menopausal hot flushes. Recommendations from the Spanish Menopause Society

  • M. Fasero,
  • M. Sanchez,
  • L. Baquedano,
  • I. Gippini,
  • D. Fuentes,
  • C. Navarro,
  • E. Beltrán,
  • M. Lilue,
  • I. Porcel,
  • C. Pingarrón,
  • M. Herrero,
  • P. Romero,
  • T. Ortega,
  • E. Carretero,
  • S. Palacios,
  • N. Mendoza,
  • P.J. Coronado

DOI
https://doi.org/10.1016/j.eurox.2025.100366
Journal volume & issue
Vol. 25
p. 100366

Abstract

Read online

This project aims to develop recommendations for treating vasomotor symptoms (VMS) based on the Cervantes short-form scale score (menopausal domain) using the best available evidence. A total of 166 studies were selected: 108 randomized controlled trials, 23 systematic reviews, 3 reviews, 3 meta-analyses, 11 case-control studies, 9 observational studies, and 12 transversal studies. To achieve this objective, a series of PICO (Patient, Intervention, Comparison, and Outcome) questions have been established for the treatment of VMS. We evaluate the quality of the scientific evidence and, with the findings, create a decision framework to treat hot flashes based on the Cervantes short-form scale score.

Keywords