Frontiers in Transplantation (Jul 2025)
Case Report: Persistent drug-resistant Pseudomonas aeruginosa infection in a young post-kidney transplant patient that proved fatal
Abstract
This case report highlights the management of recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) Pseudomonas aeruginosa in a post-renal transplant patient. Despite the challenges posed by antibiotic resistance, the patient was successfully treated with an extended infusion of meropenem, underscoring the efficacy of this approach in such difficult cases. The patient's recurrent infections required multiple hospitalizations and adjustments in treatment protocols, including the use of alternative antibiotics like fosfomycin and tailored immunosuppressive management to control both infection and rejection. This case is noteworthy for demonstrating the successful management of recurrent UTIs in the immunocompromised patient population, providing valuable insights into the treatment strategies that can be employed in similar clinical scenarios.
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