Infection and Drug Resistance (Sep 2021)

Lifestyle and Comorbidity-Related Risk Factors of Severe and Critical COVID-19 Infection: A Comparative Study Among Survived COVID-19 Patients in Bangladesh

  • Mohsin FM,
  • Nahrin R,
  • Tonmon TT,
  • Nesa M,
  • Tithy SA,
  • Saha S,
  • Mannan M,
  • Shahjalal M,
  • Faruque MO,
  • Hawlader MDH

Journal volume & issue
Vol. Volume 14
pp. 4057 – 4066

Abstract

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Faroque Md Mohsin,1,2 Ridwana Nahrin,2 Tajrin Tahrin Tonmon,2 Maherun Nesa,3 Sharmin Ahmed Tithy,1 Shuvajit Saha,4 Mahmudul Mannan,5 Md Shahjalal,2 Mohammad Omar Faruque,6 Mohammad Delwer Hossain Hawlader2 1Directorate General of Health Services, Ministry of Health and Family Welfare, Dhaka, Bangladesh; 2Department of Public Health, North South University, Dhaka, Bangladesh; 3Department of Surgery, Sheikh Hasina National Institute of Burn & Plastic Surgery, Dhaka, Bangladesh; 4Department of Maternal and Child Health, Projahnmo Research Foundation, Dhaka, Bangladesh; 5Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; 6Department of Botany, University of Chittagong, Chattogram, BangladeshCorrespondence: Mohammad Delwer Hossain HawladerDepartment of Public Health, North South University, Dhaka, 1229, BangladeshEmail [email protected]: Severe COVID-19 infections have already taken more than 4 million lives worldwide. Factors, such as socio-demographics, comorbidities, lifestyles, environment, and so on, have been widely discussed to be associated with increased severity in many countries. The study aimed to determine the risk factors of severe–critical COVID-19 in Bangladesh.Methods: This was a comparative cross-sectional study among various types of COVID-19 patients (both hospitalized and non-hospitalized) confirmed by reverse transcription polymerase chain reaction (RT-PCR). We have selected 1500 COVID-19 positive patients using a convenient sampling technique and analyzed lifestyle and comorbidity-related data using IBM SPSS-23 statistical package software. Chi-square test and multinomial logistic regression were used to determine risk factors of life-threatening COVID-19 infection.Results: The mean age of the study participants was 43.23 (± 15.48) years. The study identified several lifestyle-related factors and common commodities as risk factors for severe–critical COVID-19. The patient’s age was one of the most important predictors, as people > 59 years were at higher risk (AOR=18.223). Among other lifestyle factors, active smoking (AOR=1.482), exposure to secondary smoking (AOR=1.728), sleep disturbance (AOR=2.208) and attachment with SLT/alcohol/substance abuse (AOR=1.804) were identified as significant predictors for severe–critical COVID-19. Patients those were overweight/obese (AOR=2.105), diabetic (AOR=4.286), hypertensive (AOR=3.363), CKD patients (AOR=8.317), asthma patients (AOR=2.152), CVD patients (AOR=7.747) were also at higher risk of severe–critical COVID-19 infection.Conclusion: This study has identified several vital lifestyles and comorbidity-related risk factors of severe–critical COVID-19. People who have these comorbidities should be under high protection, and risky lifestyles of the general population should modify through the proper educational campaign.Keywords: COVID-19, lifestyle, comorbidities, risk factor, Bangladesh

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