EClinicalMedicine (May 2024)
Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study
- Xue Bai,
- Ahmed Shaheen,
- Charlotte Grieco,
- Paolo D. d’Arienzo,
- Florentia Mina,
- Juliane A. Czapla,
- Aleigha R. Lawless,
- Eleonora Bongiovanni,
- Umberto Santaniello,
- Helena Zappi,
- Dominika Dulak,
- Andrew Williamson,
- Rebecca Lee,
- Avinash Gupta,
- Caili Li,
- Lu Si,
- Martina Ubaldi,
- Naoya Yamazaki,
- Dai Ogata,
- Rebecca Johnson,
- Benjamin C. Park,
- Seungyeon Jung,
- Gabriele Madonna,
- Juliane Hochherz,
- Yoshiyasu Umeda,
- Yasuhiro Nakamura,
- Christoffer Gebhardt,
- Lucia Festino,
- Mariaelena Capone,
- Paolo Antonio Ascierto,
- Douglas B. Johnson,
- Serigne N. Lo,
- Georgina V. Long,
- Alexander M. Menzies,
- Kenjiro Namikawa,
- Mario Mandala,
- Jun Guo,
- Paul Lorigan,
- Yana G. Najjar,
- Andrew Haydon,
- Pietro Quaglino,
- Genevieve M. Boland,
- Ryan J. Sullivan,
- Andrew J.S. Furness,
- Ruth Plummer,
- Keith T. Flaherty
Affiliations
- Xue Bai
- Department of Melanoma and Sarcoma, Peking University Cancer Hospital & Institute, China; Massachusetts General Hospital, USA; Corresponding author. Department of Melanoma and Sarcoma, Peking University Cancer Hospital & Institute, China.
- Ahmed Shaheen
- Newcastle University Centre for Cancer, UK
- Charlotte Grieco
- Skin Unit, The Royal Marsden NHS Foundation Trust, London, UK
- Paolo D. d’Arienzo
- Skin Unit, The Royal Marsden NHS Foundation Trust, London, UK
- Florentia Mina
- Skin Unit, The Royal Marsden NHS Foundation Trust, London, UK
- Juliane A. Czapla
- Massachusetts General Hospital, USA
- Aleigha R. Lawless
- Massachusetts General Hospital, USA
- Eleonora Bongiovanni
- Dermatologic Clinic, Department of Medical Sciences, University of Turin Medical School, Italy
- Umberto Santaniello
- Dermatologic Clinic, Department of Medical Sciences, University of Turin Medical School, Italy
- Helena Zappi
- Alfred Health, Australia
- Dominika Dulak
- Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
- Andrew Williamson
- The Christie NHS Foundation Trust, Manchester, UK
- Rebecca Lee
- Division of Cancer Sciences, University of Manchester and Christie NHS Foundation Trust, Manchester, UK
- Avinash Gupta
- The Christie NHS Foundation Trust, Manchester, UK
- Caili Li
- Department of Melanoma and Sarcoma, Peking University Cancer Hospital & Institute, China
- Lu Si
- Department of Melanoma and Sarcoma, Peking University Cancer Hospital & Institute, China
- Martina Ubaldi
- University of Perugia, Italy
- Naoya Yamazaki
- Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo, Japan
- Dai Ogata
- Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo, Japan
- Rebecca Johnson
- Melanoma Institute Australia, The University of Sydney; Faculty of Medicine and Health, The University of Sydney; Department of Medical Oncology, Royal North Shore and Mater Hospitals, Sydney, Australia
- Benjamin C. Park
- Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
- Seungyeon Jung
- Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
- Gabriele Madonna
- Department of Melanoma, Cancer Immunotherapy and Development Therapeutics - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Italy
- Juliane Hochherz
- Department of Dermatology, University Medical Center Hamburg-Eppendorf (UKE), University Skin Cancer Center, Hamburg, Germany
- Yoshiyasu Umeda
- Department of Skin Oncology/Dermatology, Comprehensive Cancer Center, Saitama Medical University International Medical Center, Saitama, Japan
- Yasuhiro Nakamura
- Department of Skin Oncology/Dermatology, Comprehensive Cancer Center, Saitama Medical University International Medical Center, Saitama, Japan
- Christoffer Gebhardt
- Department of Dermatology, University Medical Center Hamburg-Eppendorf (UKE), University Skin Cancer Center, Hamburg, Germany
- Lucia Festino
- Department of Melanoma, Cancer Immunotherapy and Development Therapeutics - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Italy
- Mariaelena Capone
- Department of Melanoma, Cancer Immunotherapy and Development Therapeutics - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Italy
- Paolo Antonio Ascierto
- Department of Melanoma, Cancer Immunotherapy and Development Therapeutics - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Italy
- Douglas B. Johnson
- Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
- Serigne N. Lo
- Melanoma Institute Australia, The University of Sydney; Faculty of Medicine and Health, The University of Sydney, North Sydney, NSW, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia
- Georgina V. Long
- Melanoma Institute Australia, The University of Sydney; Faculty of Medicine and Health, The University of Sydney; Department of Medical Oncology, Royal North Shore and Mater Hospitals, Sydney, Australia
- Alexander M. Menzies
- Melanoma Institute Australia, The University of Sydney; Faculty of Medicine and Health, The University of Sydney; Department of Medical Oncology, Royal North Shore and Mater Hospitals, Sydney, Australia
- Kenjiro Namikawa
- Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo, Japan
- Mario Mandala
- University of Perugia, Italy
- Jun Guo
- Department of Melanoma and Sarcoma, Peking University Cancer Hospital & Institute, China
- Paul Lorigan
- Division of Cancer Sciences, University of Manchester and Christie NHS Foundation Trust, Manchester, UK
- Yana G. Najjar
- UPMC Hillman Cancer Center, Pittsburgh, PA, USA
- Andrew Haydon
- Alfred Health, Australia
- Pietro Quaglino
- Dermatologic Clinic, Department of Medical Sciences, University of Turin Medical School, Italy
- Genevieve M. Boland
- Massachusetts General Hospital, USA
- Ryan J. Sullivan
- Massachusetts General Hospital, USA
- Andrew J.S. Furness
- Skin Unit, The Royal Marsden NHS Foundation Trust, London, UK
- Ruth Plummer
- Newcastle University Centre for Cancer, UK
- Keith T. Flaherty
- Massachusetts General Hospital, USA; Corresponding author.
- Journal volume & issue
-
Vol. 71
p. 102564
