FDA approved drugs as potential Ebola treatments [v2; ref status: indexed, http://f1000r.es/554]

Abstract

In the search for treatments for the Ebola Virus, multiple screens of FDA drugs have led to the identification of several with promising in vitro activity. These compounds were not originally developed as antivirals and some have been further tested in mouse in vivo models. We put forward the opinion that some of these drugs could be evaluated further and move into the clinic as they are already FDA approved and in many cases readily available. This may be important if there is a further outbreak in future and no other therapeutic is available.

Keywords

• Antimicrobials & Drug Resistance
• Drug Discovery & Design
• Tropical & Travel-Associated Diseases
• Virology