Synthesis and Preliminary Characterization of a New Hexadentate Sequestrant in the Ethylenediaminetetrapropionic Acid Class

Abstract

Ethylenediaminetetraacetic acid (EDTA) (E-385) as such and/or derivatized (salified) occupies a separate chapter, of wide interest in food sciences, because of its coordinating (sequestering) competences towards various organic and/or inorganic structures (especially metal cations) with small geometric dimensions. This paper aims to diversify the structural range of these hexadentate ligands, by accessing a synthetic protocol different from the classic one, the cyanoethylation of primary amine functional groups of ethylenediamine (ED). In this paper are considered the main dependences of the yields of nucleophilic addition of the amino groups to the activated double bond in acrylonitrile (AN) monomer, on the operating parameters (temperature, processing time, molar ratio of reactants), and finally the preliminary data on the coordinating (sequestering) competence of ethylenediaminetetrapropionic acid (EDTP). The conclusions drawn support further research to extend the area of hexadentate sequestering structures.

Keywords

• hexadentate ligands
• complexone ii
• ethylenediaminetetraacetic acid
• trilon b
• n,n'-bis-(2-hydroxyethyl)-ethylenediamine-n,n'-diacetic acid