Increased serum levels of Bisphenol A and Betatrophin in patients

Abstract

Psoriasis is a common and serious systemic inflammatory disease. The purpose of this study is to research the relationship between bisphenol A, betatrophin, urocortin 3 and vitamin D levels in patients with psoriasis. Sixty patients with psoriasis (mean age, 34.1±9.6 years) and twenty six age and gender-matched healthy individuals (mean age, 35.5 ±10.5 years) were included in this study. Bisphenol A, betatrophin, urocortin 3 and vitamin D levels were assessed by using enzyme-linked immunosorbent assay in all participants. Serum levels of bisphenol A were detected using UPLC-ESI-MS/MS. In psoriasis patients, the median bisphenol A serum level was 0.537 ng/mL (range 1.1), and significantly higher compared to controls (median 0.2 range 0.9 ng/mL) (p [Med-Science 2018; 7(3.000): 580-6]

Keywords

• Psoriasis
• bisphenol A
• betatrophin
• urocortin 3
• vitamin D