Methotrexate Treatment of Newly Diagnosed RA Patients Is Associated With DNA Methylation Differences at Genes Relevant for Disease Pathogenesis and Pharmacological Action

• Kari Guderud,
• Kari Guderud,
• Line H. Sunde,
• Line H. Sunde,
• Siri T. Flåm,
• Siri T. Flåm,
• Marthe T. Mæhlen,
• Maria D. Mjaavatten,
• Ellen S. Norli,
• Ida M. Evenrød,
• Bettina K. Andreassen,
• Sören Franzenburg,
• Andre Franke,
• Simon Rayner,
• Kristina Gervin,
• Kristina Gervin,
• Kristina Gervin,
• Benedicte A. Lie,
• Benedicte A. Lie

Affiliations

Kari Guderud

Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway

Kari Guderud

K. G. Jebsen Inflammation Research Centre, University of Oslo, Oslo, Norway

Line H. Sunde

Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway

Line H. Sunde

K. G. Jebsen Inflammation Research Centre, University of Oslo, Oslo, Norway

Siri T. Flåm

Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway

Siri T. Flåm

K. G. Jebsen Inflammation Research Centre, University of Oslo, Oslo, Norway

Marthe T. Mæhlen

Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

Maria D. Mjaavatten

Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

Ellen S. Norli

Department of Rheumatology, Martina Hansens Hospital, Bærum, Norway

Ida M. Evenrød

Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway

Bettina K. Andreassen

Department of Research, Cancer Registry of Norway, Institute for Population-Based Research, Oslo, Norway

Sören Franzenburg

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany

Andre Franke

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany

Simon Rayner

Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway

Kristina Gervin

Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway

Kristina Gervin

PharmaTox Strategic Research Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway

Kristina Gervin

Division of Clinical Neuroscience, Department of Research and Innovation, Oslo University Hospital, Oslo, Norway

Benedicte A. Lie

Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway

Benedicte A. Lie

K. G. Jebsen Inflammation Research Centre, University of Oslo, Oslo, Norway