Nature Communications (May 2021)

Programming gene expression in multicellular organisms for physiology modulation through engineered bacteria

  • Baizhen Gao,
  • Qing Sun

DOI
https://doi.org/10.1038/s41467-021-22894-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 8

Abstract

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Manipulating animal physiology can be difficult because of the complexity of multicellular systems. Here the authors use engineered bacteria to modulate Caenorhabditis elegans gene expression through genetic circuit controlled RNAi.