567 Merkel cell carcinomas are infiltrated by tumor-associated macrophages that counteract intratumoral CD8 T-cell benefit and correlate with resistence to PD-1 pathway blockade

• Paul Nghiem,
• Rima Kulikauskas,
• Daniel S Hippe,
• Xinyi Fan,
• Kimberly S Smythe,
• Ata Moshiri,
• Thomas Pulliam,
• Shira Tabachnick-Cherny,
• Haroldo Rodriguez Chevez,
• Kelly Paulson,
• Daniel C Jones,
• Lisa Zaba

Affiliations

Paul Nghiem

1University of Washington, Seattle, WA, USA

Rima Kulikauskas

1University of Washington, Seattle, WA, USA

Daniel S Hippe

2Fred Hutchinson Cancer Center, Seattle, WA, USA

Xinyi Fan

2Fred Hutchinson Cancer Center, Seattle, WA, USA

Kimberly S Smythe

2Fred Hutchinson Cancer Center, Seattle, WA, USA

Ata Moshiri

3New York University, New York, NY, USA

Thomas Pulliam

1University of Washington, Seattle, WA, USA

Shira Tabachnick-Cherny

1University of Washington, Seattle, WA, USA

Haroldo Rodriguez Chevez

1University of Washington, Seattle, WA, USA

Kelly Paulson

5Swedish Cancer Institute, Edmonds, WA, USA

Daniel C Jones

2Fred Hutchinson Cancer Center, Seattle, WA, USA

Lisa Zaba

4Stanford University School of Medicine, Palo Alto, CA, USA