Direct dehydrogenative alkyl Heck-couplings of vinylarenes with umpolung aldehydes catalyzed by nickel

Abstract

Heck coupling of alkenes with organic halides, arenes or organometallics poses sustainability issues due to hazardous waste formation and use of oxidants. Here, the authors show an oxidant-free alkyl Heck-coupling of vinylarenes with umpolung aldehydes, liberating H2, N2 and H2O as sole side products.