Deliod a lightweight detection model for intestinal organoids based on deep learning

Abstract

Abstract Intestinal organoids are indispensable tools for exploring intestinal disorders. Deep learning methodologies are often employed in morphological analysis to evaluate the condition of these organoids. Nonetheless, prevailing analytical techniques face obstacles such as many organisational overlaps and tiny targets lead to a high incidence of errors and limited applicability. This paper presents Deliod, a streamlined intestinal organoid detection model founded on YOLOv8 and designed to automate the identification of organoid morphology. Deliod performed excellently compared to leading detection models when applied to an intestinal organoid dataset, attaining an mAP50 of 87.5%. Ablation experiments verified the module’s efficacy in improving detection performance. Furthermore, Deliod features a modest parameter count of 5.41 M and a computational load of 16.6 GFLOPs, facilitating the broader application of the detection model in the realm of intestinal organoid image recognition. This streamlined model not only enables efficient and accurate recognition of organoid morphology but also minimizes hardware deployment requirements, broadening its range of potential applications.

Keywords

• Intestinal organoids
• Deep learning
• YOLOv8s
• Morphological analysis
• Lightweight