PLoS ONE (Jan 2021)

Determinants of late detection and advanced-stage diagnosis of breast cancer in Nigeria.

  • Olayide Agodirin,
  • Samuel Olatoke,
  • Ganiyu Rahman,
  • Oladapo Kolawole,
  • Saliu Oguntola,
  • Olalekan Olasehinde,
  • Omobolaji Ayandipo,
  • Julius Olaogun,
  • Aba Katung,
  • Amarachukwu Etonyeaku,
  • Olufemi Habeeb,
  • Ademola Adeyeye,
  • John Agboola,
  • Halimat Akande,
  • Olusola Akanbi,
  • Oluwafemi Fatudimu,
  • Anthony Ajiboye

DOI
https://doi.org/10.1371/journal.pone.0256847
Journal volume & issue
Vol. 16, no. 11
p. e0256847

Abstract

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ObjectiveTo describe the risk factors for late detection and advanced-stage diagnosis among patients who detected their BC early.MethodUsing secondary data, we analyzed the impact of socio-demographic factors, premorbid experience, BC knowledge, and health-seeking pattern on the risk of late detection and advanced-stage diagnosis after early BC detection. Test of statistical significance in SPSS and EasyR was set at 5% using Sign-test, chi-square tests (of independence and goodness of fit), odds ratio, or risk ratio as appropriate.ResultMost socio-demographic factors did not affect detection size or risk of disease progression in the 405 records analyzed. High BC knowledge, p-value = 0.001, and practicing breast self-examination (BSE) increased early detection, p-value = 0.04, with a higher probability (OR 1.6 (95% CI 1.1-2.5) of detecting ConclusionStrategies to increase BC knowledge and BSE may help BC downstaging, especially among women with common barriers to early diagnosis.