CAAI Transactions on Intelligence Technology (Jun 2025)

Needle detection and localisation for robot‐assisted subretinal injection using deep learning

  • Mingchuan Zhou,
  • Xiangyu Guo,
  • Matthias Grimm,
  • Elias Lochner,
  • Zhongliang Jiang,
  • Abouzar Eslami,
  • Juan Ye,
  • Nassir Navab,
  • Alois Knoll,
  • Mohammad Ali Nasseri

DOI
https://doi.org/10.1049/cit2.12242
Journal volume & issue
Vol. 10, no. 3
pp. 703 – 715

Abstract

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Abstract Subretinal injection is a complicated task for retinal surgeons to operate manually. In this paper we demonstrate a robust framework for needle detection and localisation in robot‐assisted subretinal injection using microscope‐integrated Optical Coherence Tomography with deep learning. Five convolutional neural networks with different architectures were evaluated. The main differences between the architectures are the amount of information they receive at the input layer. When evaluated on ex‐vivo pig eyes, the top performing network successfully detected all needles in the dataset and localised them with an Intersection over Union value of 0.55. The algorithm was evaluated by comparing the depth of the top and bottom edge of the predicted bounding box to the ground truth. This analysis showed that the top edge can be used to predict the depth of the needle with a maximum error of 8.5 μm.

Keywords