Dalbavancin for Successful Treatment of Infective Endocarditis Caused by Enterococcus faecalis

Abstract

Infective endocarditis is a relatively uncommon infection that requires a high index of suspicion, which can sometimes delay its diagnosis. It requires several weeks of intravenous antibiotics, which traditionally requires long hospital stays. Dalbavancin is a novel antibiotic with high activity against several Gram-positive pathogens. Its weekly administration allows the outpatient management of complicated infections requiring parenteral treatment, but only a few cases of Enterococcus faecalis endocarditis treated with dalbavancin have been reported in the literature. We here report a case of successful treatment with dalbavancin of an infectious endocarditis caused by E. faecalis.

Keywords

• infective endocarditis
• dalbavancin
• enterococcus
• outpatient parenteral antimicrobial therapy
• opat