Genome-Scale Metabolic Model of
<i>Caldicellulosiruptor bescii</i>
Reveals Optimal Metabolic Engineering Strategies for Bio-based Chemical Production

mSystems (Jun 2021)

Affiliations

Ke Zhang: Department of Cell and Molecular Biology, College of the Environment and Life Sciences, University of Rhode Island, Kingston, Rhode Island, USA
Weishu Zhao: Department of Cell and Molecular Biology, College of the Environment and Life Sciences, University of Rhode Island, Kingston, Rhode Island, USA
Dmitry A. Rodionov: Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, California, USA
Gabriel M. Rubinstein: Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA
Diep N. Nguyen: Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA
Tania N. N. Tanwee: Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA
James Crosby: Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA
Ryan G. Bing: Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA
Robert M. Kelly: Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA
Michael W. W. Adams: ORCiD; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA
Ying Zhang: ORCiD; Department of Cell and Molecular Biology, College of the Environment and Life Sciences, University of Rhode Island, Kingston, Rhode Island, USA

Abstract

The extremely thermophilic cellulolytic bacterium, Caldicellulosiruptor besciiC. bescii